20VC: Inside Carnegie Mellon's $4BN Endowment | Why 90% of LPs Shouldn't Invest in VC | The $140BN Problem with Multi-Stage Funds | The Hidden Math Behind DPI, TVPI, and Illiquidity with Miles Dieffenbach
2025-08-04 · 87 min · 13 entities
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20VC: Inside Carnegie Mellon's $4BN Endowment | Why 90% of LPs Shouldn't Invest in VC | The $140BN Problem with Multi-Stage Funds | The Hidden Math Behind DPI, TVPI, and Illiquidity with Miles Dieffenbach
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20VC: Inside Carnegie Mellon's $4BN Endowment | Why 90% of LPs Shouldn't Invest in VC | The $140BN Problem with Multi-Stage Funds | The Hidden Math Behind DPI, TVPI, and Illiquidity with Miles Dieffenbach
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20VC: Inside Carnegie Mellon's $4BN Endowment | Why 90% of LPs Shouldn't Invest in VC | The $140BN Problem with Multi-Stage Funds | The Hidden Math Behind DPI, TVPI, and Illiquidity with Miles Dieffenbach
Episode description as stored
Miles Dieffenbach is Managing Director of Investments at Carnegie Mellon University, where he helps oversee a $4 billion endowment with a focus on venture capital, private equity, and alternative investments. Under his leadership, CMU's private book has remained self-funding during some of the toughest years for liquidity.
Agenda for Today:
00:04 – "I Had Cancer at 26 – It Changed Everything"
07:00 – Inside the $4BN Carnegie Mellon Endowment: The Investment Blueprint
10:45 – Are LPs Getting Screwed in Venture?
13:30 – 90% of LPs Shouldn't Be in Venture – Here's Why
16:00 – Seed Funds Are a Trap (And No One Wants to Admit It)
20:00 – The $140BN Problem with Multi-Stage Funds
24:00 – "Index Is the Best in the Game – Here's Why They Win"
29:30 – "The Dirty Secret of LPs: Brand Over Performance"
34:30 – "When Founder-Friendly Goes Too Far"
38:00 – "The OpenAI Bubble – Will It All Go to Zero?"
44:00 – "Ping Pong Diligence & Wildest Fundraising Stories"