Dr. Zach Bush: How the Microbiome Affects Metabolism, Brain Health, and Chronic Disease
2026-08-13 · 75 min · episode 89 · 14 entities
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Link in episode "Dr. Zach Bush: How the Microbiome Affects Metabolism, Brain Health, and Chronic Disease": https://farmersfootprint.us/
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Episode description as stored
Join The Circle and use code "PODCAST": https://holplus.co/circle/ What if chronic disease, declining energy, cognitive issues, and fertility challenges are not isolated problems, but signs of a deeper disconnection from the natural world?
In this episode of hol+ with Dr. Taz MD, Dr. Zach Bush explores the relationship between human health and the health of our environment. Drawing from his background in internal medicine, endocrinology, cancer research, and hospice care, he explains how his search for the root causes of disease led him from the hospital and laboratory to the microbiome, soil science, and regenerative agriculture.
Dr. Bush describes mitochondria as essential generators of cellular energy and explains how the microbes living within and around us help support metabolism, immunity, neurological function, and communication throughout the body. He shares his perspective on how chemical agriculture, declining biodiversity, and changes in our food systems may be affecting these biological relationships.
Dr. Taz and Dr. Bush also discuss the rise of obesity, insulin resistance, autoimmune disease, cognitive decline, chronic fatigue, and infertility. Dr. Bush presents his theory that these conditions may be connected through a broader decline in metabolic energy and our increasing separation from nature.
The conversation ultimately turns toward hope and practical action. Dr. Bush explains why restoring soil, supporting regenerative farmers, growing food, strengthening local communities, and spending more time in direct contact with nature may help rebuild both human and planetary health. He also shares how something as simple as growing a mint plant can begin restoring a family’s relationship with living food.
In this episode:
Dr. Bush’s journey from conventional medicine to microbiome and soil research
What mitochondria do and why they are essential for cellular energy
How the microbiome influences metabolism, immunity, and brain function
The relationship between soil health, food quality, and human health
How chemical agriculture may disrupt biological communication
Why Dr. Bush describes modern illness as nature deficit disorder
His theory connecting metabolic decline with chronic disease and fertility
Why supplements cannot fully replace a healthy food system
How regenerative agriculture can support human and planetary health
Simple ways to reconnect your family with food, soil, and nature
Why community and human connection may be essential parts of healing
About Dr. Zach Bush:
Dr. Zach Bush is a triple board-certified physician specializing in internal medicine, endocrinology and metabolism, and hospice and palliative care. His work has focused on the relationships between the microbiome, human health, environmental health, food systems, and regenerative agriculture.
After years of working in conventional medicine and biomedical research, Dr. Bush began exploring how soil health, biodiversity, and chemical exposure may influence human metabolism and chronic disease. His work helped give rise to Project Biome and Farmer’s Footprint, initiatives focused on regenerative food systems and restoring the relationship between human and planetary health.
Connect with Dr. Zach Bush:
https://zachbushmd.com/
https://www.instagram.com/zachbushmd/
https://farmersfootprint.us/
About Dr. Taz:
Dr. Tasneem Bhatia (Dr. Taz) is a triple board-certified integrative medicine physician, bestselling author, and founder of hol+, a multi-location integrative medicine practice.
Learn more: https://doctortaz.com/about
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