168. Chemistry, Evolved
2025-10-11 · 57 min · episode 168 · 4 entities
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Feed category: Society & Culture
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evidence rules-v4
Feed author/publisher: Freakonomics Radio + Stitcher
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companys 2
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evidence rules-v4
Feed author/publisher: Freakonomics Radio + Stitcher
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evidence rules-v4
Feed author/publisher: Freakonomics Radio + Stitcher
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Feed category: Society & Culture
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evidence rules-v4
Feed category: Society & Culture
Episode description as stored
Frances Arnold pioneered the process of directed evolution — mimicking natural selection to create new enzymes that have changed everything from agriculture to laundry.
SOURCES: Frances Arnold , professor of chemistry at the California Institute of Technology.
RESOURCES: " Innovation by Evolution: Bringing New Chemistry to Life ," by Frances Arnold (Nobel Lecture, 2018).
" Bacteria taught to bond carbon and silicon for the first time ," by Aviva Rutkin ( New Scientist , 2016).
" Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life ," by S. B. Jennifer Kan, Russell D. Lewis, Kai Chen, and Frances H. Arnold ( Science , 2016).
" The Director of Evolution ," by Jennifer Ouellette ( Slate , 2013).
" Engineered ketol-acid reductoisomerase and alcohol dehydrogenase enable anaerobic 2-methylpropan-1-ol production at theoretical yield in Escherichia coli ," by Sabine Bastian, Xiang Liu, Joseph T. Meyerowitz, Christopher D. Snow, Mike M. Y. Chen, and Frances H. Arnold ( Metabolic Engineering , 2011).
Gevo .
Provivi .
EXTRAS: " How to Help Kids Succeed ," by People I (Mostly) Admire (2025).
The Levitt Lab .
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