What It Takes to Build a Startup | Andrew Chen & Matt Perault

2026-09-11 · 38 min · episode 1195 · 12 entities

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What It Takes to Build a Startup | Andrew Chen & Matt Perault
discusses Science concept

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discusses Technology concept

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discusses Business concept

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discusses Entrepreneurship concept

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Episode description as stored

a16z’s Matt Perault sits down with General Partner and Speedrun lead Andrew Chen on the a16z AI Policy Brief to explore what “Little Tech” actually looks like at the earliest stages, and why the realities of building a two- or three-person startup are often missing from policy debates. Andrew takes us inside Speedrun, where founders are often starting companies from kitchen tables, working with tiny teams, and trying to determine in a matter of months whether their idea can become a viable business. He explains why these founders rarely have the time or resources to engage with policymakers, even as regulation can have an outsized impact on whether and where they build. Matt and Andrew also discuss how regulatory burdens accumulate for young companies, why startups can choose where to put down roots, the role of ecosystems like Tech Week, and what policymakers can do to hear directly from the founders who may otherwise be absent from the conversation. This episode originally appeared on the a16z AI Policy Brief. Resources: Follow Andrew Chen on X: https://x.com/andrewchen Follow Matt Perault on X: https://x.com/MattPerault Learn more about a16z Speedrun: https://speedrun.a16z.com Listen to more from the a16z AI Policy Brief : https://a16zpolicy.substack.com/ Stay Updated: Find a16z on YouTube: YouTube Find a16z on X Find a16z on LinkedIn Listen to the a16z Show on Spotify Listen to the a16z Show on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.