Big Ideas 2026: The Enterprise Orchestration Layer

2025-12-23 · 22 min · episode 997 · 22 entities

episode page audio

Asserted relationships

→ references A16z Podcast podcast

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evidence rules-v4
Link in episode "Big Ideas 2026: The Enterprise Orchestration Layer": https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711
→ references Seema Amble person

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evidence rules-v4
Link in episode "Big Ideas 2026: The Enterprise Orchestration Layer": https://x.com/seema_amble
→ hosted by Andreessen Horowitz person

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Feed author/publisher: Andreessen Horowitz
→ discusses Science concept

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Feed category: Science
→ discusses Technology concept

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Feed category: Technology
→ discusses Business concept

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Feed category: Business
→ discusses Entrepreneurship concept

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Feed category: Entrepreneurship
→ hosted by a16z company

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Feed author/publisher: a16z
→ references Big Ideas 2026 Part 1 website

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Link in episode "Big Ideas 2026: The Enterprise Orchestration Layer": https://a16z.com/newsletter/big-ideas-2026-part-1
→ references Big Ideas 2026 Part 2 website

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evidence rules-v4
Link in episode "Big Ideas 2026: The Enterprise Orchestration Layer": https://a16z.com/newsletter/big-ideas-2026-part-2
→ references Big Ideas 2026 Part 3 website

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evidence rules-v4
Link in episode "Big Ideas 2026: The Enterprise Orchestration Layer": https://a16z.com/newsletter/big-ideas-2026-part-3

Entities found in this episode

concepts 9

mentioned Science concept

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Feed category: Science
mentioned Technology concept

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Feed category: Technology
mentioned Business concept

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Feed category: Business
mentioned Entrepreneurship concept

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Feed category: Entrepreneurship
mentioned The Enterprise Orchestration Layer concept

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evidence rules-v4
Big Ideas 2026: The Enterprise Orchestration Layer
discusses Science concept

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evidence rules-v4
Feed category: Science
discusses Technology concept

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evidence rules-v4
Feed category: Technology
discusses Business concept

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evidence rules-v4
Feed category: Business
discusses Entrepreneurship concept

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evidence rules-v4
Feed category: Entrepreneurship

websites 6

mentioned Big Ideas 2026 Part 1 website

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evidence rules-v4
Link in episode "Big Ideas 2026: The Enterprise Orchestration Layer": https://a16z.com/newsletter/big-ideas-2026-part-1
mentioned Big Ideas 2026 Part 2 website

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evidence rules-v4
Link in episode "Big Ideas 2026: The Enterprise Orchestration Layer": https://a16z.com/newsletter/big-ideas-2026-part-2
mentioned Big Ideas 2026 Part 3 website

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evidence rules-v4
Link in episode "Big Ideas 2026: The Enterprise Orchestration Layer": https://a16z.com/newsletter/big-ideas-2026-part-3
references Big Ideas 2026 Part 1 website

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evidence rules-v4
Link in episode "Big Ideas 2026: The Enterprise Orchestration Layer": https://a16z.com/newsletter/big-ideas-2026-part-1
references Big Ideas 2026 Part 2 website

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evidence rules-v4
Link in episode "Big Ideas 2026: The Enterprise Orchestration Layer": https://a16z.com/newsletter/big-ideas-2026-part-2
references Big Ideas 2026 Part 3 website

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evidence rules-v4
Link in episode "Big Ideas 2026: The Enterprise Orchestration Layer": https://a16z.com/newsletter/big-ideas-2026-part-3

persons 4

mentioned Seema Amble person

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evidence rules-v4
Link in episode "Big Ideas 2026: The Enterprise Orchestration Layer": https://x.com/seema_amble
references Seema Amble person

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evidence rules-v4
Link in episode "Big Ideas 2026: The Enterprise Orchestration Layer": https://x.com/seema_amble
mentioned Andreessen Horowitz person

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Feed author/publisher: Andreessen Horowitz
hosted by Andreessen Horowitz person

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evidence rules-v4
Feed author/publisher: Andreessen Horowitz

podcasts 2

mentioned A16z Podcast podcast

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evidence rules-v4
Link in episode "Big Ideas 2026: The Enterprise Orchestration Layer": https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711
references A16z Podcast podcast

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evidence rules-v4
Link in episode "Big Ideas 2026: The Enterprise Orchestration Layer": https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711

companys 1

hosted by a16z company

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Feed author/publisher: a16z

Episode description as stored

AI is becoming the orchestration layer inside the enterprise. In this episode of Big Ideas 2026, we explore the shift from isolated AI copilots to coordinated multi-agent systems that plan, analyze, and execute work across teams and tools. This is not a new feature, but a new way workflows run inside large organizations. You will hear from Seema Amble on context extraction and coordinated agent teams, Angela Strange on why unified data and parallel workflows accelerate core replacement, Alex Immerman on multiplayer AI and execution boundaries, and David Haber on what makes these systems commercially defensible. Together, these perspectives define the enterprise orchestration layer: not a chatbot and not a standalone tool, but a coordinated system of agents that runs the workflow and delivers real outcomes across the business. Resources: Follow Angela Strange on X: https://x.com/astrange Follow David Haber on X: https://x.com/dhaber Follow Alex Immerman on X: https://x.com/aleximm Follow Seema Amble on X: https://x.com/seema_amble Read more all of our 2026 Big Ideas Part 1: https://a16z.com/newsletter/big-ideas-2026-part-1 Part 2: https://a16z.com/newsletter/big-ideas-2026-part-2/ Part 3: https://a16z.com/newsletter/big-ideas-2026-part-3/ Stay Updated: If you enjoyed this episode, be sure to like, subscribe, and share with your friends! Find a16z on X: https://twitter.com/a16z Find a16z on LinkedIn: https://www.linkedin.com/company/a16z Listen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYX Listen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711 Follow our host: https://x.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated: Find a16z on YouTube: YouTube Find a16z on X Find a16z on LinkedIn Listen to the a16z Show on Spotify Listen to the a16z Show on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.