Why You're So Bloated on Ozempic
2026-08-13 · 14 min · episode 227 · 17 entities
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Feed author/publisher: Dr. Gabrielle Lyon
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Link in episode "Why You're So Bloated on Ozempic": https://tiktok.com/@drgabriellelyon
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Link in episode "Why You're So Bloated on Ozempic": https://foreverstrong.supercast.com/
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Link in episode "Why You're So Bloated on Ozempic": https://drgabriellelyon.com/new-patient-inquiry
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Link in episode "Why You're So Bloated on Ozempic": https://tiktok.com/@drgabriellelyon
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Link in episode "Why You're So Bloated on Ozempic": https://foreverstrong.supercast.com/
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Link in episode "Why You're So Bloated on Ozempic": https://tiktok.com/@drgabriellelyon
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Link in episode "Why You're So Bloated on Ozempic": https://foreverstrong.supercast.com/
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Feed author/publisher: Dr. Gabrielle Lyon
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Feed author/publisher: Dr. Gabrielle Lyon
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Link in episode "Why You're So Bloated on Ozempic": https://drgabriellelyon.com/new-patient-inquiry
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Link in episode "Why You're So Bloated on Ozempic": https://drgabriellelyon.com/new-patient-inquiry
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Why You're So Bloated on Ozempic
Episode description as stored
You might think the number dropping on the scale is the whole win, but on a GLP-1, a meaningful share of what you're losing may be muscle, not fat, and the fiber that's supposed to help can quietly make things worse.
In this solo episode, Dr. Gabrielle Lyon discusses:
Why 25–40% of the weight lost on GLP-1 medications can be lean mass, and how to protect your muscle with adequate protein (1.2–1.5 g/kg) and resistance training
The GLP-1 fiber paradox and why these drugs need fiber to work, but make it hard to tolerate, and why 40–70% of patients hit GI side effects like bloating and constipation
When to fiber max vs. fiber mine, plus how to reintroduce fiber gradually so you get the gut benefits without the bloat, bezoars, or obstruction risk
Get this balance right, and you keep your muscle, calm your gut, and let the medication do its job instead of ending up bloated, constipated, and quietly losing strength.
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Chapters
00:00 - Introduction
00:46 - The pear bezoar and bowel obstruction
02:07 - Why 95% of Americans fall short
03:32 - The GLP-1 fiber paradox
04:18 - Why GLP-1 drugs make fiber hard to eat
05:50 - How GLP-1s slow the gut
07:40 - Bezoars, psyllium, and the 87-case series
09:12 - Fiber as therapy: titrating it right
10:03 - The muscle loss problem
11:28 - Getting the fiber and GLP-1 balance right
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Disclaimers: This episode includes paid sponsorships.
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