World Model · podcast knowledge graph

#19 - Dave Feldman: stress testing the lipid energy model

2018-10-08 · 190 min · episode 19 · 11 entities

episode page audio

Asserted relationships

  • → appeared on The Peter Attia Drive podcast
    0.68
    evidence rules-v4
    #19 - Dave Feldman: stress testing the lipid energy model
  • → hosted by Peter Attia, MD person
    0.55
    evidence rules-v4
    Feed author/publisher: Peter Attia, MD
  • → discusses Health & Fitness concept
    0.40
    evidence rules-v4
    Feed category: Health & Fitness
  • → discusses Medicine concept
    0.40
    evidence rules-v4
    Feed category: Medicine
  • → discusses Fitness concept
    0.40
    evidence rules-v4
    Feed category: Fitness

Entities found in this episode

concepts 7

  • mentioned Health & Fitness concept
    0.50
    evidence rules-v4
    Feed category: Health & Fitness
  • mentioned Medicine concept
    0.50
    evidence rules-v4
    Feed category: Medicine
  • mentioned Fitness concept
    0.50
    evidence rules-v4
    Feed category: Fitness
  • 0.42
    evidence rules-v4
    #19 - Dave Feldman: stress testing the lipid energy model
  • discusses Health & Fitness concept
    0.40
    evidence rules-v4
    Feed category: Health & Fitness
  • discusses Medicine concept
    0.40
    evidence rules-v4
    Feed category: Medicine
  • discusses Fitness concept
    0.40
    evidence rules-v4
    Feed category: Fitness

persons 3

  • mentioned Peter Attia, MD person
    0.70
    evidence rules-v4
    Feed author/publisher: Peter Attia, MD
  • mentioned Dave Feldman person
    0.70
    evidence rules-v4
    #19 - Dave Feldman: stress testing the lipid energy model
  • hosted by Peter Attia, MD person
    0.55
    evidence rules-v4
    Feed author/publisher: Peter Attia, MD

podcasts 1

  • appeared on The Peter Attia Drive podcast
    0.68
    evidence rules-v4
    #19 - Dave Feldman: stress testing the lipid energy model
Episode description as stored
In this episode, Dave Feldman, discusses his journey from software engineer to n=1 experimenter, his experience with low-carbohydrate diets, and his hypothesis that cholesterol levels are influenced by energy metabolism.   We discuss: Peter's synthesis of Dave's energy model [ 5:00 ]; Dave's journey from software engineer to cholesterol enthusiast [ 15:00 ]; Standard blood panels, sterol panels, and what moves the needle when it comes to particle numbers [ 18:30 ]; Hyper-responders [ 20:00 ]; Lipoprotein transport [33:45]; The lean mass hyper-responder phenotype [47:30]; The progression of atherosclerosis, CAC, and CIMT [52:30]; Testing for oxidized LDL [55:30]; All-cause mortality and clinical endpoints [1:01:15]; What does "LDL as causal" mean? [1:05:15]; Dave's low carb cholesterol challenge and drug & genetic study qualifications [1:13:15]; If all other markers are in an healthy range, but LDL-P is high, is the patient at risk? A couple of case studies, and a self-experiment [1:27:30]; Peter's three-day exercise and ketosis experiment [ 1:41:00 ]; What are remnant lipoproteins? [ 1:45:00 ]; What might cause lean mass hyper-responders to have higher LDL particle numbers? [1:53:30]; A case study from Dave of a lean mass hyper-responder [1:56:30]; Mass balance and cholesterol flux [2:05:30]; Can a higher degree of cholesterol explain the lean mass hyper-responder phenotype? [ 2:10:00 ]; Peter's LDL during his keto-fast-keto experiment [2:13:30]; Does substituting saturated fats with monounsaturated fats lower LDL-P and LDL-C? [2:15:45]; Dave's carb-swap experiments [2:22:15]; Dave's carotid intima-media thickness tests [2:41:15]; Looking for studies that stratify for high HDL-C and low TG alongside low and high LDL-C [ 2:53:00 ]; and More Learn more at  www.PeterAttiaMD.com Connect with Peter on Facebook | Twitter | Instagram .