#02 - Rhonda Patrick, Ph.D.: the performance and longevity paradox of IGF-1, ketogenic diets and genetics, the health benefits of sauna, NAD+, and more

2018-07-02 · 110 min · episode 2 · 10 entities

episode page audio

Asserted relationships

→ hosted by Peter Attia, MD person

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evidence rules-v4
Feed author/publisher: Peter Attia, MD
→ discusses Health & Fitness concept

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Feed category: Health & Fitness
→ discusses Medicine concept

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Feed category: Medicine
→ discusses Fitness concept

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Feed category: Fitness

Entities found in this episode

concepts 8

mentioned Health & Fitness concept

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evidence rules-v4
Feed category: Health & Fitness
mentioned Medicine concept

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evidence rules-v4
Feed category: Medicine
mentioned Fitness concept

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Feed category: Fitness
discusses Health & Fitness concept

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evidence rules-v4
Feed category: Health & Fitness
discusses Medicine concept

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evidence rules-v4
Feed category: Medicine
discusses Fitness concept

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evidence rules-v4
Feed category: Fitness
mentioned NAD concept

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NAD
mentioned IGF concept

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IGF

persons 2

mentioned Peter Attia, MD person

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evidence rules-v4
Feed author/publisher: Peter Attia, MD
hosted by Peter Attia, MD person

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evidence rules-v4
Feed author/publisher: Peter Attia, MD

Episode description as stored

Rhonda and I go on a Nerd Safari into the jungle of health, nutrition, fitness, performance, and longevity. We visit IGF-1 and whether there's a tradeoff of having high or low levels. We discuss the PPARs (receptor proteins) and genetic polymorphisms. Does Rhonda think there's any benefit in a NAD+ booster for health and longevity? Can saunas lower the risk of heart disease, dementia, and all-cause mortality? Rhonda is a wealth of knowledge on so many topics and was the perfect companion to dig into so many fun topics in this episode. She puts a ton of thought into her research and it really shows in this conversation. We discuss: What Rhonda believes differently today than she did a few years ago [5:40]; The paradox of GH/IGF-1 in performance and longevity [21:00]; The role of PPAR in fat metabolism and ketogenic diets [23:00]; The possible genetic explanations for why some patients don't respond well to a ketogenic diet [31:00]; The health benefits of heat and cold exposure [1:12:30]; NAD+ [1:32:45]; And more. Learn more at www.PeterAttiaMD.com Connect with Peter on Facebook | Twitter | Instagram