Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515

2026-08-07 · 11 min · episode 1515 · 38 entities

episode page audio

Asserted relationships

→ references Articles website

0.77

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://nature.com/articles/s41514-026-00383-9
→ references pubmed.ncbi.nlm.nih.gov concept

0.77

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://pubmed.ncbi.nlm.nih.gov/42294499
→ hosted by Dave Asprey person

0.55

evidence rules-v5
Feed author/publisher: Dave Asprey
→ discusses Education concept

0.40

evidence rules-v5
Feed category: Education
→ discusses Science concept

0.40

evidence rules-v5
Feed category: Science
→ discusses Health & Fitness concept

0.40

evidence rules-v5
Feed category: Health & Fitness
→ discusses Self-Improvement concept

0.40

evidence rules-v5
Feed category: Self-Improvement
→ references News Releases person

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://eurekalert.org/news-releases/1137190
→ references switchsupplements.com website

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://switchsupplements.com/
→ references Eat Less Protein Age Better Live Longer website

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://time.com/article/2026/08/03/eat-less-protein-age-better-live-longer
→ references Cell Reports Blue person

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://cell.com/cell-reports-blue/fulltext/S2949-8821(26
→ references The Hottest New Anti Aging Treatment Cadaver Skin website

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://nypost.com/2026/07/21/health/the-hottest-new-anti-aging-treatment-cadaver-skin
→ references Elravie Re2o Application website

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://laboderm-skin.com/elravie-re2o-application
→ references Study Arts Slow Biological Aging person

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://npr.org/2026/05/12/nx-s1-5818172/study-arts-slow-biological-aging
→ references Regular Arts Engagement May Help Slow Biological Aging Process website

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://news-medical.net/news/20260511/Regular-arts-engagement-may-help-slow-biological-aging-process.aspx
→ references Arts Culture May Slow Aging person

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://studyfinds.com/arts-culture-may-slow-aging
→ references 06 Popular Glp Drug Biological Aging website

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://medicalxpress.com/news/2026-06-popular-glp-drug-biological-aging.html
→ references Semaglutide May Slow Epigenetic Aging In Humans website

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://creativebiomart.net/blog/semaglutide-may-slow-epigenetic-aging-in-humans
→ references Can You Reverse Epigenetic Age person

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://superpower.com/guides/can-you-reverse-epigenetic-age

Entities found in this episode

websites 16

references Articles website

0.77

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://nature.com/articles/s41514-026-00383-9
mentioned Articles website

0.45

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://pmc.ncbi.nlm.nih.gov/articles/PMC8991228
mentioned switchsupplements.com website

0.45

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://switchsupplements.com/
mentioned Eat Less Protein Age Better Live Longer website

0.45

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://time.com/article/2026/08/03/eat-less-protein-age-better-live-longer
mentioned The Hottest New Anti Aging Treatment Cadaver Skin website

0.45

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://nypost.com/2026/07/21/health/the-hottest-new-anti-aging-treatment-cadaver-skin
mentioned Elravie Re2o Application website

0.45

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://laboderm-skin.com/elravie-re2o-application
mentioned Regular Arts Engagement May Help Slow Biological Aging Process website

0.45

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://news-medical.net/news/20260511/Regular-arts-engagement-may-help-slow-biological-aging-process.aspx
mentioned 06 Popular Glp Drug Biological Aging website

0.45

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://medicalxpress.com/news/2026-06-popular-glp-drug-biological-aging.html
mentioned Semaglutide May Slow Epigenetic Aging In Humans website

0.45

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://creativebiomart.net/blog/semaglutide-may-slow-epigenetic-aging-in-humans
references switchsupplements.com website

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://switchsupplements.com/
references Eat Less Protein Age Better Live Longer website

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://time.com/article/2026/08/03/eat-less-protein-age-better-live-longer
references The Hottest New Anti Aging Treatment Cadaver Skin website

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://nypost.com/2026/07/21/health/the-hottest-new-anti-aging-treatment-cadaver-skin
references Elravie Re2o Application website

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://laboderm-skin.com/elravie-re2o-application
references Regular Arts Engagement May Help Slow Biological Aging Process website

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://news-medical.net/news/20260511/Regular-arts-engagement-may-help-slow-biological-aging-process.aspx
references 06 Popular Glp Drug Biological Aging website

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://medicalxpress.com/news/2026-06-popular-glp-drug-biological-aging.html
references Semaglutide May Slow Epigenetic Aging In Humans website

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://creativebiomart.net/blog/semaglutide-may-slow-epigenetic-aging-in-humans

persons 12

mentioned Dave Asprey person

0.70

evidence rules-v5
Feed author/publisher: Dave Asprey
hosted by Dave Asprey person

0.55

evidence rules-v5
Feed author/publisher: Dave Asprey
mentioned News Releases person

0.45

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://eurekalert.org/news-releases/1137190
mentioned Cell Reports Blue person

0.45

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://cell.com/cell-reports-blue/fulltext/S2949-8821(26
mentioned Study Arts Slow Biological Aging person

0.45

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://npr.org/2026/05/12/nx-s1-5818172/study-arts-slow-biological-aging
mentioned Arts Culture May Slow Aging person

0.45

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://studyfinds.com/arts-culture-may-slow-aging
mentioned Can You Reverse Epigenetic Age person

0.45

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://superpower.com/guides/can-you-reverse-epigenetic-age
references News Releases person

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://eurekalert.org/news-releases/1137190
references Cell Reports Blue person

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://cell.com/cell-reports-blue/fulltext/S2949-8821(26
references Study Arts Slow Biological Aging person

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://npr.org/2026/05/12/nx-s1-5818172/study-arts-slow-biological-aging
references Arts Culture May Slow Aging person

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://studyfinds.com/arts-culture-may-slow-aging
references Can You Reverse Epigenetic Age person

0.38

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://superpower.com/guides/can-you-reverse-epigenetic-age

concepts 10

mentioned pubmed.ncbi.nlm.nih.gov concept

0.90

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://pubmed.ncbi.nlm.nih.gov/42294499
references pubmed.ncbi.nlm.nih.gov concept

0.77

evidence rules-v5
Link in episode "Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515": https://pubmed.ncbi.nlm.nih.gov/42294499
mentioned Education concept

0.50

evidence rules-v5
Feed category: Education
mentioned Science concept

0.50

evidence rules-v5
Feed category: Science
mentioned Health & Fitness concept

0.50

evidence rules-v5
Feed category: Health & Fitness
mentioned Self-Improvement concept

0.50

evidence rules-v5
Feed category: Self-Improvement
discusses Education concept

0.40

evidence rules-v5
Feed category: Education
discusses Science concept

0.40

evidence rules-v5
Feed category: Science
discusses Health & Fitness concept

0.40

evidence rules-v5
Feed category: Health & Fitness
discusses Self-Improvement concept

0.40

evidence rules-v5
Feed category: Self-Improvement

Episode description as stored

Subtitle: A Nasal Spray Longevity Screen, Why Less Protein May Age You Better, Cadaver Skin Injectables, Art's Effect on Biological Age, and Which Anti-Aging Interventions Actually Move the Needle Nasal Spray Ingredient Emerges As Unexpected Longevity Candidate In Massive Drug Screen Researchers mapped 2,358 longevity-associated genes across the body's broader protein and signaling networks, then screened 6,442 approved drugs to see which ones nudged those aging pathways in a healthier direction. Oxymetazoline, the active ingredient in nasal sprays like Afrin, was among 21 standout candidates, with a predicted pathway running through the ACKR3 receptor and connecting to major aging proteins including NF-kB, TP53, and AKT1. Host Dave Asprey explains why this computational screen is a promising research lead rather than a protocol, and why chronic use of a vasoconstricting nasal spray carries real risks regardless of what a network analysis suggests. Sources: https://www.inc.com/lucia-auerbach/scientists-screened-6442-drugs-for-longevity-common-nasal-spray-emerged-as-a-surprising-candidate/91381000 https://www.sciencealert.com/medications-already-in-pharmacies-may-slow-aging-and-scientists-are-narrowing-them-down https://pmc.ncbi.nlm.nih.gov/articles/PMC12425021/ ~~ New Review Of 350+ Studies Asks Whether Less Protein Means Longer Life A review spanning more than 350 studies found that protein restriction consistently extended lifespan and improved metabolic health across mice, rats, flies, and fish, with smaller human studies showing improvements in body fat and fasting glucose even when total calorie intake rose. Researchers point to FGF21, a liver hormone that rises under protein or amino acid scarcity and boosts energy expenditure and glucose regulation, as a key mechanism. Host Dave Asprey breaks down why blanket protein advice fails older adults preserving muscle and highly active people just as badly as it fails everyone else, and why matching intake to actual biology beats maximizing protein at every meal. Sources: https://www.medicalnewstoday.com/articles/why-reducing-protein-intake-could-promote-healthy-aging-new-research https://time.com/article/2026/08/03/eat-less-protein-age-better-live-longer/ https://www.sciencedaily.com/releases/2026/08/260801042811.htm https://www.cell.com/cell-reports-blue/fulltext/S2949-8821(26)00079-9 https://pmc.ncbi.nlm.nih.gov/articles/PMC8991228/ https://www.eurekalert.org/news-releases/1137190 ~~ Processed Cadaver Skin Injectable Enters The Anti-Aging Market As Elravie Re2O A new injectable called Elravie Re2O, short for "return to your 20s," is made from donated human skin processed to remove living cells and most genetic material, leaving a collagen-rich extracellular matrix that gets injected into the face and neck as a biological scaffold rather than a simple filler. Human-derived tissue matrices already have a track record in burn and wound care, but this specific product is not yet FDA-approved and lacks comparative trial data against existing fillers. Host Dave Asprey separates legitimate regenerative medicine from a novel cosmetic product still waiting on long-term safety and consistency data. Sources: https://nypost.com/2026/07/21/health/the-hottest-new-anti-aging-treatment-cadaver-skin/ https://www.newsobserver.com/living/article316698211.html https://www.miamiherald.com/living/article316698295.html https://pmc.ncbi.nlm.nih.gov/articles/PMC12985180/ https://laboderm-skin.com/elravie-re2o-application/ ~~ UCL Study Finds Weekly Arts Engagement Tracks With Slower Epigenetic Aging A University College London study of more than 3,500 adults found that people who engaged weekly with arts and culture, including painting, music, museums, and theater, showed a roughly four percent slower pace of aging on the DunedinPACE clock and appeared about one biological year younger on PhenoAge, with the effect holding after adjusting for income, education, smoking, and physical activity. Bene