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#062 Dr. Steve Horvath on epigenetic aging to predict healthspan: the DNA PhenoAge and GrimAge clocks

2020-12-22 · 94 min · 10 entities

Asserted relationships

  • → hosted by Rhonda Patrick, Ph.D person
    0.55
    evidence rules-v5
    Feed author/publisher: Rhonda Patrick, Ph.D.
  • → discusses Health & Fitness concept
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    evidence rules-v5
    Feed category: Health & Fitness
  • → discusses Nutrition concept
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    evidence rules-v5
    Feed category: Nutrition
  • → discusses Medicine website
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    evidence rules-v5
    Feed category: Medicine

Entities found in this episode

concepts 6

  • mentioned Health & Fitness concept
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    evidence rules-v5
    Feed category: Health & Fitness
  • mentioned Nutrition concept
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    evidence rules-v5
    Feed category: Nutrition
  • 0.42
    evidence rules-v5
    #062 Dr. Steve Horvath on epigenetic aging to predict healthspan: the DNA PhenoAge and GrimAge clocks
  • discusses Health & Fitness concept
    0.40
    evidence rules-v5
    Feed category: Health & Fitness
  • discusses Nutrition concept
    0.40
    evidence rules-v5
    Feed category: Nutrition
  • mentioned DNA concept
    0.35
    evidence rules-v5
    DNA

persons 2

  • mentioned Rhonda Patrick, Ph.D person
    0.70
    evidence rules-v5
    Feed author/publisher: Rhonda Patrick, Ph.D.
  • hosted by Rhonda Patrick, Ph.D person
    0.55
    evidence rules-v5
    Feed author/publisher: Rhonda Patrick, Ph.D.

websites 2

  • mentioned Medicine website
    0.50
    evidence rules-v5
    Feed category: Medicine
  • discusses Medicine website
    0.40
    evidence rules-v5
    Feed category: Medicine
Episode description as stored
Steve Horvath Steve Horvath, PhD, is a professor of human genetics and biostatistics at UCLA's Fielding School of Public Health Dr. Steve Horvath has analyzed large data sets of DNA methylation profiles to derive an algorithm that accurately predicts a person's chronological age across multiple cells, tissues, and organs, and even mammalian species. He built on this algorithm to develop second-generation clocks that could predict time-to-death among people of the same chronological age, as well as lifespan and healthspan. In this episode, we discuss: (00:00)  Introduction and overview (20:24)  Horvath Aging Clocks (26:36)  Heredity determines aging (35:49)  DNAm PhenoAge vs GrimAge (45:58)  Slowing the epigenetic clock (01:10:43)  Epigenetics: Cause or consequence of aging? (01:16:43)  Vitamin D reverses epigenetic age (01:19:07)  Omega-3 slows GrimAge clock (01:24:19)  Ongoing research If you're interested in learning more, you can read the full show notes here . Join over 300,000 people and get the latest distilled information on aging straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor