#040 Dr. Eric Verdin on Ketogenic Diet Longevity, Beta-Hydroxybutyrate & HDAC Inhibitors

2017-12-13 · 63 min · 10 entities

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→ hosted by Rhonda Patrick, Ph.D person

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Feed author/publisher: Rhonda Patrick, Ph.D.
→ works at Medicine website

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professor of Medicine
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→ discusses Nutrition concept

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evidence rules-v5
Feed category: Nutrition
→ discusses Medicine website

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evidence rules-v5
Feed category: Medicine

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mentioned Health & Fitness concept

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evidence rules-v5
Feed category: Health & Fitness
mentioned Nutrition concept

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evidence rules-v5
Feed category: Nutrition
discusses Health & Fitness concept

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evidence rules-v5
Feed category: Health & Fitness
discusses Nutrition concept

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evidence rules-v5
Feed category: Nutrition
mentioned HDAC concept

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HDAC

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mentioned Medicine website

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evidence rules-v5
Feed category: Medicine
works at Medicine website

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professor of Medicine
discusses Medicine website

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evidence rules-v5
Feed category: Medicine

persons 2

mentioned Rhonda Patrick, Ph.D person

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evidence rules-v5
Feed author/publisher: Rhonda Patrick, Ph.D.
hosted by Rhonda Patrick, Ph.D person

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evidence rules-v5
Feed author/publisher: Rhonda Patrick, Ph.D.

Episode description as stored

Eric M. Verdin Eric M. Verdin, M.D. is the fifth president and chief executive officer of the Buck Institute for Research on Aging and is a professor of Medicine at UCSF. Dr. Verdin's laboratory focuses on the role of epigenetic regulators in the aging process, the role of metabolism and diet in aging and on the chronic diseases of aging, including Alzheimer's, proteins that play a central role in linking caloric restriction to increased healthspan, and more recently a topic near and dear to many of you, ketogenesis. He's held faculty positions at the University of Brussels, the NIH and the Picower Institute for Medical Research. In this episode, you'll discover: (00:00) Introduction (07:32) Interventions to prolong lifespan (10:42) The role of insulin pathways in aging (16:25) HDAC inhibition by ketones (27:52) Protein activates mTOR & IGF-1 (30:28) PPAR-alpha activation facilitates benefits of a ketogenic diet (35:28) What biomarkers can predict aging? (39:38) Cellular NAD+ levels decrease with age (52:47) Ketogenic diet safety (56:07) Intermittent fasting as an alternative to a keto diet If you're interested in learning more, you can read the full show notes here . Join over 300,000 people and get the latest distilled information on ketogenic diet & longevity straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor